Professor, Associate Professor of Psychiatry and Neurology, Georgetown University Medical Center; Director, Huntington's Disease Care, Education, and Research Center, MedStar Georgetown University Hospital, Washington, DCServe as a consultant for: Azevan Pharmaceuticals ; Roche/Biogen ; Teva ; T Austedo and temper outbursts at the patient's mother's end of life . The patient was referred to a neurologist for a comprehensive workup.
Grade 0: No gross abnormalities or neuropathologic histology despite clinical evidence of HD. There may be up to 30%-40% reduction in neuronal number in the head of the caudate. Grade 2: Some atrophy of the caudate with enlargement of the lateral ventricles, although the ventricular surface maintains its convex shape. The globus pallidus begins to show degeneration.