May 30 2024University of Notre Dame Urinary catheters are required for nearly every surgical procedure. However, a major challenge for the health care industry is predicting who may develop catheter-associated urinary tract infections and when these infections may lead to death.
Fibrin is vital in the formation of blood clots when the body attempts to repair injuries. When injured, the body calls on a process that uses fibrin to repair a wound, creating a fibrous structure to prevent bleeding during the healing process. However, when the researchers blocked fibrinogen recruitment or accumulation, it reduced CAUTIs because the pathogens needed the fibrin net-like structure to survive and persist.
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